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Skin loses more than collagen. It loses biological coordination.

Healthy skin isn't built one ingredient at a time.

It's the result of billions of biological conversations happening every second.

As we age. those conversations become quieter.

THE PAIRING

He discovered the complete signal. She proved it on patients.

Laura Ellis, MD
Surgeon • Molecular Biologist • Co-Founder

Hans Keirstead, PhD
Stem-Cell Scientist • Inventor

PROVOQUE™ delivers the complete skin secretome—the molecular conversation skin cells use to communicate, restore, and renew.

Built on a rare partnership in regenerative aesthetics: a stem-cell scientist who spent three decades capturing the complete biological signal, and a surgeon who spent four years demonstrating what happens when skin regains its biological coordination with PROVOQUE™.

DERMATOLOGIST-ASSESSED

97% Improvement at 12 weeks

Improvement in roughness, softness & fine lines.

Reference: Nistor G, Poole AJ,DraelosZ, et al. Human Stem Cell-Derived Skin Progenitors Produce Alpha 2-HS Glycoprotein (Fetuin): A Revolutionary Cosmetic Ingredient. J Drugs Dermatol. 2016;15(5):583-598.​

12 Weeks of Use

Photos courtesy of Winston Salem Dermatology

Before

After

Use the left and right arrow keys to navigate between before and after photos.

Photographs courtesy of Authorized PROVOQUE™ Providers. Images are presented as submitted and have not been digitally retouched by PROVOQUE. Patients used PROVOQUE Facial Serum only. Individual results may vary.